ATIC antibody

Catalog No. ABIN2716431

The Mouse Monoclonal anti-ATIC antibody has been validated for WB and FACS. It is suitable to detect ATIC in samples from Human, Mouse, Rat, Dog and Monkey.

Quick Overview for ATIC antibody (ABIN2716431)

Target: ATIC (5-Aminoimidazole-4-Carboxamide Ribonucleotide Formyltransferase/IMP Cyclohydrolase (ATIC))

Reactivity: Human, Mouse, Rat, Dog, Monkey

Host: Mouse

Clonality: Monoclonal

Conjugate: This ATIC antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS)

Clone: 1D2

Product Details anti-ATIC Antibody

Characteristics: Homo sapiens 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase (ATIC)

Purification: Purified from mouse ascites fluids by affinity chromatography

Immunogen: Full length human recombinant protein of human ATIC(NP_004035) produced in HEK293T cell.

Isotype: IgG1

Application Details

Application Notes: WB 1:500~2000, FLOW 1:100,

Comment:

The concentration of the product may vary between diferrent lots.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5-1.0 mg/mL

Buffer: PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for ATIC

Target: ATIC (5-Aminoimidazole-4-Carboxamide Ribonucleotide Formyltransferase/IMP Cyclohydrolase (ATIC))

Alternative Name: ATIC

Background: This gene encodes a bifunctional protein that catalyzes the last two steps of the de novo purine biosynthetic pathway. The N-terminal domain has phosphoribosylaminoimidazolecarboxamide formyltransferase activity, and the C-terminal domain has IMP cyclohydrolase activity. A mutation in this gene results in AICA-ribosiduria.

Molecular Weight: 64.4 kDa

Gene ID: 471

NCBI Accession: NM_004044

HGNC: 471